PyScript has actually been massively refactored in the last few months and is much faster now. You can check the performance of PyScript running MicroPython her

PyScript has actually been massively refactored in the last few months and is much faster now. You can check the performance of PyScript running MicroPython here: https://laffra.github.io/ltk/ https://laffra.github.io/ltk/ If you need/choose Pyodide load time will of course by much more but that's mostly because of the size of full core Python and the dependencies you might have.