3 ms·
Dimethyl fumarate is not an antifungal drug. It's an immunomodulator.
by atombender 3y ago
Dimethyl fumarate is not an antifungal drug. It's an immunomodulator.
- abirch 3y agoYou're correct it's not an antifungal drug, it's a substance used for its antifungal properties. Furniture companies today still use it for that: https://www.leatherusa.org/dimethyl-fumarate-dmf https://www.leatherusa.org/dimethyl-fumarate-dmf you can Google "Dimethyl fumarate furniture". I'm not sure if it's mechanism of action is known. It was originally used to prevent mold on furniture. The Germans notices that treated psoriasis when it was applied topically. After which the swiss(Fumapharm) was noticed that people who took it for psoriasis and had MS, had fewer MS symptoms. https://en.wikipedia.org/wiki/Dimethyl_fumarate https://en.wikipedia.org/wiki/Dimethyl_fumarate ==== https://pubmed.ncbi.nlm.nih.gov/36641891 https://pubmed.ncbi.nlm.nih.gov/36641891 Dimethyl fumarate ameliorates fungal keratitis by limiting fungal growth and inhibiting pyroptosis