> the viruses you're referring to weren't isolated They're made de novo (adenovirus and baculovirus derivatives, and yes, I've done this for baculovirus), whic

> the viruses you're referring to weren't isolated They're made de novo (adenovirus and baculovirus derivatives, and yes, I've done this for baculovirus), which is better than isolation as even with isolation it's difficult to prove a pure sample. Even Koch couldn't prove an isolated sample back in the day. Not to our standards, at least. Throw a GFP protein in the modified adenovirus or baculovirus genome and you can literally see the exact specific virus that you made move from cell to cell while the cells start dying.