3 ms·

It'll be great to learn more about these and see what diseases are associated with them. I still think it's crazy that an anti-fungal drug is very good therapeu

by abirch 3y ago

It'll be great to learn more about these and see what diseases are associated with them. I still think it's crazy that an anti-fungal drug is very good therapeutic for Multiple Sclerosis: https://en.m.wikipedia.org/wiki/Dimethyl_fumarate https://en.m.wikipedia.org/wiki/Dimethyl_fumarate

Paul-Craft 3y ago
Are you lost? You don't seem to have read the same article I just did.
- abirch 3y ago
  "It’s not yet known whether obelisks affect human health, says Matthew Sullivan, an integrative biologist at Ohio State University" We have no idea what these do. What if they could cause MS? Then drugs could kill these things and prevent MS. Now that we know some cancers are caused by viruses, we've created vaccines to stop the viruses and the cancer.
  - a_gnostic 3y ago
    It is probably best to destroy obelisks, and deny their utility to the Necrontyr.
- hinkley 3y ago
  We don’t know why human digestion is such a (pun not intended) shitshow right now. There are microbes that don’t culture in agar. There are histamine reactions from allergies. Detergents and rinse agents messing up protective layers. Or maybe the right bacteria are there but they’re sick with a virus and misbehaving. We don’t know. My brain went the same place as GP but without the anecdote. So I suspect did the people who greyed out your reply before I got here.
  - deleted 3y ago
    [deleted]
- coldtea 3y ago
  Or he just paid attention to it: "It’s not yet known whether obelisks affect human health, says Matthew Sullivan, an integrative biologist at Ohio State University, but they could alter the genetic activity of their bacterial hosts, which in turn could affect human genes." And of course, even if there wasn't an explicit reference to that question, wondering how those new entities might affect our health is 100% compatible with the article.
panabee 3y ago
not fungal, but pathogen related: stanford researchers in 2022 identified how epstein-barr virus (EBV) could be one cause of MS. essentially, EBV proteins may mimic a human protein and induce the immune system to mistakenly attack the body’s nerve cells. https://med.stanford.edu/news/all-news/2022/01/epstein-barr-virus-multiple-sclerosis.html https://med.stanford.edu/news/all-news/2022/01/epstein-barr-...
atombender 3y ago
Dimethyl fumarate is not an antifungal drug. It's an immunomodulator.
- abirch 3y ago
  You're correct it's not an antifungal drug, it's a substance used for its antifungal properties. Furniture companies today still use it for that: https://www.leatherusa.org/dimethyl-fumarate-dmf https://www.leatherusa.org/dimethyl-fumarate-dmf you can Google "Dimethyl fumarate furniture". I'm not sure if it's mechanism of action is known. It was originally used to prevent mold on furniture. The Germans notices that treated psoriasis when it was applied topically. After which the swiss(Fumapharm) was noticed that people who took it for psoriasis and had MS, had fewer MS symptoms. https://en.wikipedia.org/wiki/Dimethyl_fumarate https://en.wikipedia.org/wiki/Dimethyl_fumarate ==== https://pubmed.ncbi.nlm.nih.gov/36641891 https://pubmed.ncbi.nlm.nih.gov/36641891 Dimethyl fumarate ameliorates fungal keratitis by limiting fungal growth and inhibiting pyroptosis

by abirch 3y ago

Paul-Craft 3y ago

Are you lost? You don't seem to have read the same article I just did.

abirch 3y ago
"It’s not yet known whether obelisks affect human health, says Matthew Sullivan, an integrative biologist at Ohio State University" We have no idea what these do. What if they could cause MS? Then drugs could kill these things and prevent MS. Now that we know some cancers are caused by viruses, we've created vaccines to stop the viruses and the cancer.
- a_gnostic 3y ago
  It is probably best to destroy obelisks, and deny their utility to the Necrontyr.
hinkley 3y ago
We don’t know why human digestion is such a (pun not intended) shitshow right now. There are microbes that don’t culture in agar. There are histamine reactions from allergies. Detergents and rinse agents messing up protective layers. Or maybe the right bacteria are there but they’re sick with a virus and misbehaving. We don’t know. My brain went the same place as GP but without the anecdote. So I suspect did the people who greyed out your reply before I got here.
- deleted 3y ago
  [deleted]
coldtea 3y ago
Or he just paid attention to it: "It’s not yet known whether obelisks affect human health, says Matthew Sullivan, an integrative biologist at Ohio State University, but they could alter the genetic activity of their bacterial hosts, which in turn could affect human genes." And of course, even if there wasn't an explicit reference to that question, wondering how those new entities might affect our health is 100% compatible with the article.

panabee 3y ago

not fungal, but pathogen related: stanford researchers in 2022 identified how epstein-barr virus (EBV) could be one cause of MS. essentially, EBV proteins may mimic a human protein and induce the immune system to mistakenly attack the body’s nerve cells. https://med.stanford.edu/news/all-news/2022/01/epstein-barr-virus-multiple-sclerosis.html https://med.stanford.edu/news/all-news/2022/01/epstein-barr-...

atombender 3y ago

Dimethyl fumarate is not an antifungal drug. It's an immunomodulator.

abirch 3y ago
You're correct it's not an antifungal drug, it's a substance used for its antifungal properties. Furniture companies today still use it for that: https://www.leatherusa.org/dimethyl-fumarate-dmf https://www.leatherusa.org/dimethyl-fumarate-dmf you can Google "Dimethyl fumarate furniture". I'm not sure if it's mechanism of action is known. It was originally used to prevent mold on furniture. The Germans notices that treated psoriasis when it was applied topically. After which the swiss(Fumapharm) was noticed that people who took it for psoriasis and had MS, had fewer MS symptoms. https://en.wikipedia.org/wiki/Dimethyl_fumarate https://en.wikipedia.org/wiki/Dimethyl_fumarate ==== https://pubmed.ncbi.nlm.nih.gov/36641891 https://pubmed.ncbi.nlm.nih.gov/36641891 Dimethyl fumarate ameliorates fungal keratitis by limiting fungal growth and inhibiting pyroptosis