3 ms·
> Ion Torrent and Genapsys are barely used due to accuracy problems, Accurancy didn't have very much to do with Ion Torrent's demise. As we're reminded in the
by ejstronge 3y ago
> Ion Torrent and Genapsys are barely used due to accuracy problems,
Accurancy didn't have very much to do with Ion Torrent's demise. As we're reminded in the OP, Illumina pushed the MiSeq platform, and there wasn't much reason to transition to Ion Torrent. Now, with 250 bp+ PE reads on Illumina, there really isn't much special about Ion Torrent besides its somewhat superior homopolymer performance.
> but Oxford Nanopore's considerable logistical benefits of tolerating a wide range of input DNA concentration, quick time to data, low capital cost, and long reads has kept them alive. Maybe they will grow more with higher accuracy.
This statement is reasonable in today's era, but ONT was nowhere close to being competitive with Ion Torrent and other platforms during the time where labs were considering the Ion Torrent devices vs continued spend on Illumina platforms.
The accuracy, tolerance to unusual DNA samples, and read length with clinically-relevant base qualities were unusable until 2018/2019.