Probably not what you're looking for, but I put together a demo of actually cross-compiling a wheel the other day: https://github.com/jvolkman/bazel-pycross-zst

Probably not what you're looking for, but I put together a demo of actually cross-compiling a wheel the other day: https://github.com/jvolkman/bazel-pycross-zstandard-example https://github.com/jvolkman/bazel-pycross-zstandard-example But if you just mean that you want to gather the dependencies for a platform other than your build host: this should be possible with the help of Poetry and PDM since they both perform cross-platform resolution.