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The Nanopore Minion is still a thing, but it's sequencing and has higher error rates than competing short-read methods like Illumina's sequence by synthesis. h
by genomer 3y ago
The Nanopore Minion is still a thing, but it's sequencing and has higher error rates than competing short-read methods like Illumina's sequence by synthesis.
https://nanoporetech.com/products/sequence/minion https://nanoporetech.com/products/sequence/minion
Sequencing DNA with nanopores: Troubles and biases
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486125/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486125/
Based on what I'm seeing from 23andMe's website they only do genotyping, not sequencing.
https://customercare.23andme.com/hc/en-us/articles/227968028-How-23andMe-Personal-Genetic-Service-Works https://customercare.23andme.com/hc/en-us/articles/227968028...
"23andMe uses genotyping, not sequencing, to analyze your DNA. Sequencing technology has not yet progressed to the point where it is feasible to sequence an entire person’s genome quickly and cheaply enough to keep costs down for consumers. It took the Human Genome Project, a consortium of multiple research labs, over 10 years to sequence the whole genomes of just a few individuals."
Edit:
https://www.23andme.com/total-health https://www.23andme.com/total-health
I guess they started providing whole exome sequencing, but I can't find information about what depth they're doing it at.
- progbits 3y agoSure I don't need a full sequence, just the bits used for health features on 23andme. Of course the closer to a full sequence the better as any future research could be used by just reading existing data. But realistically just having data on few hundred most useful markers is enough.