You can read more on this here: https://academic.oup.com/nar/article/51/D1/D1512/6814452 https://academic.oup.com/nar/article/51/D1/D1512/6814452 Yes there ar

You can read more on this here: https://academic.oup.com/nar/article/51/D1/D1512/6814452 https://academic.oup.com/nar/article/51/D1/D1512/6814452 Yes there are general challenges in research, but not sure how that really changes the argument that there's significant amounts of research in this area and novel peer-reviewed findings.