3 ms·
> This is in contrast to a trained animal that has already undergone synaptic remodeling. If you have the appropriate synapses but were somehow able to remove a
by RaftPeople 3y ago
> This is in contrast to a trained animal that has already undergone synaptic remodeling. If you have the appropriate synapses but were somehow able to remove all the relevant RNA in an instant, the animal would continue to 'remember' its training. Synapses are sufficient.
Not if you removed the DNA. Epigenetic changes to the DNA are what maintain the synapse at it's "learned" state. Here's a link:
https://www.sciencedirect.com/science/article/pii/S2405844022035800 https://www.sciencedirect.com/science/article/pii/S240584402...
In addition, research has shown neurons communicating via mRNA (surrounded by a lipid).
https://www.nature.com/articles/d41586-018-00492-w https://www.nature.com/articles/d41586-018-00492-w
https://www.inverse.com/article/40113-arc-protein-ancient-mouse-brain-rna-capsid https://www.inverse.com/article/40113-arc-protein-ancient-mo...
Lots of interesting stuff in this arena.
- RaftPeople 3y agoAdditional note: I forgot that synapses are also maintained by local RNA (local=at/near the synapse), so removing the RNA would definitely cause the synapse to revert back to a different state and not retained it's "learned" state.