3 ms·
What makes nanopore screening quality worse? Aren't these long read sequencers that are supposed to read more of the DNA strand?
by darkerside 3y ago
What makes nanopore screening quality worse? Aren't these long read sequencers that are supposed to read more of the DNA strand?
- jhbadger 3y agoThe problem with Nanopore (which I've used for some projects) is that the per-base accuracy is still quite low. This can be helped to a degree by either high coverage (basically sequencing the same area over and over again with the hope that the errors are stochastic and will be corrected if you take the "average" base at each position) or combining it with shorter read but higher quality data from Illumina.