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How cheaply do you think you can run a clinical trial with human patients in the absence of bureaucracy? I imagine increased insurance and recruitment costs wou
by stdbrouw 3y ago
How cheaply do you think you can run a clinical trial with human patients in the absence of bureaucracy? I imagine increased insurance and recruitment costs would eat up the difference.
- concordDance 3y agoI expect we could empirically look at how much trials cost 50 years ago on the assumption there has been a regulatory ratchet effect. I don't know how to find that data though...
- jimberlage 3y agoA confounder here is that diseases targeting common ailments (pain, colds, etc.) have already been developed. The FDA requires that new medications be better than the existing ones one some axis. So before, you had to find people with pain. Then, you had to find women with pain. Then, you have to find pregnant women with pain. Then, you have to find pregnant women also suffering from gestational diabetes with pain. That’s hypothetical, but it’s a real trend. Costs go up based on the number of people you have to sift through to find someone eligible. Things like viagra (10 years ago) or ozempic are still in the honeymoon period where inclusion/exclusion criteria are broad enough that you can enroll lots of people in any given place.