Personally, I do not believe the benefits outweigh the risks unless you have cluster headaches or treatment resistant depression (without anxiety). Most of wha

Personally, I do not believe the benefits outweigh the risks unless you have cluster headaches or treatment resistant depression (without anxiety). Most of what people consider to be “profound” during tripping is just the drug making you think things are profound - in the same way alcohol makes you think it’s reasonable to get angry about an argument about a TV show or cocaine makes you think Uber for cats is the next trillion dollar company. It unquestionably does put you in a state where you may have ideas or thought patterns you won’t have otherwise so there’s a chance that those ideas are actually profound, just like your cocaine-fueled startup idea actually may be a good one. But people ascribe too much meaning and magic to this IMO, it’s not all it’s cracked up to be. Some people, like myself, have had panic attacks (“bad trips”) on psychedelics. Without going into detail these can be very disconcerting and leave lingering effects like PTSD/anxiety. If you are prone to anxiety I would not partake, and personally I think the benefits don’t outweigh the risk of this at all for most people. At the very least I caution against mixing LSD with cannabis, recommend you have someone with you that isn’t tripping, and ideally have something on hand to treat a panic attack (even if just strong beer/wine/liquor). A lot of people will say that 1. This only happens if you get something else passed off as acid, or have a bad set and setting 2. You can avoid that if you are smart about where you get it. I think that’s BS because it’s a well documented phenomenon and testing can only easily rule out certain particular things anyway (you can only ever be certain about it if you made it yourself or got it from a regulated research source). Similarly, LSD has the potential to induce psychosis and schizophrenia, which many say is only possible if you were going to develop those conditions anyway (it was already latent) - which is nondisprovable and has no way of being identified. Personally I think these arguments are made from a place of wishful thinking that it can’t happen to them. On the other hand single trips have been shown/known to help pull people out of depressive states in a moderately durable manner. You may not only process feelings or concepts you haven’t before, but the drug itself may induce a good mood lasting a few days called an “afterglow” which could bring you out of some kind of local optimum. If depression has been negatively impacting your quality of life for a long time I would consider the potential benefits to outweigh the risks enough to try it once. Also, cluster headaches I believe are uniquely treatable by psychedelics. Those are the only thing that I think justifies adding it to a “regimen” because IIUC those headaches are so uniquely extreme and debilitating.