2 or 3, depending on definition of regimen, but also "best" depends on what you're shooting for/concerned about. From what evidence I've reviewed it seems prett

2 or 3, depending on definition of regimen, but also "best" depends on what you're shooting for/concerned about. From what evidence I've reviewed it seems pretty low-risk from a health perspective, as long as you're taking prudent doses with prudent infrequency, and the effects are generally positive although somewhat inconsistently so. If you're curious about taking it, I would recommend doing so and picking between 2 and 3 afterwards. If you have a lot of anxiety around drug use, or are generally averse to intoxication, it might be better to stick to 1 as I think you will find the experience overwhelming. Regardless I would recommend not hyping up the experience too much in your mind, as IMO the actual 'tripping' experience on a standard 1 tab dose is quite different (and in some ways more mild) than the typical media representation, and I think too much fantasizing about what it's like can lead to more anxiety than is really necessary. Finally, I would recommend not taking more than 100ug in almost any circumstances, as IMO beyond that point the downsides start to accumulate far faster than the upsides. Some background/trip-reporting-ish: For the last 6 months or so I've been dosing around 25-50 micrograms at a frequency of ~1 per 2 weeks as my "going out" drug, rather than consuming alcohol. Results have been mixed, definitely enjoyed some nights very much but others the effects were similar to pot paranoia. Lately I've decided that this is probably an imprudent frequency and am dropping down to maybe once per quarter, but will likely consume closer to 100ug per a session. The things I like about it are: * the rush of energy that persists for the first few hours * the duration of the trip (4-6 hours of effects, which from a bang/buck perspective is a plus in my book) * the general silly vibe it creates in me. Things I don't like about it are: * the high body load (it creates a lot of muscle tension in my body, and I often feel physically worn out the next day like I was working out) * the occasional paranoia/in-my-headness * the higher level of emotional vulnerability I feel while at peak trip (good for some social situations, but in the wrong environment kind of sucks). tl;dr: on the best trips I turn into a silly fae with a lot of curiosity and humor, on the worst trips I turn into an analytical gargoyle perched at the fringes of the function. In all cases I'm kind of run down the next day.