The structure comes from having a consistent configuration of the bond angles. Most proteins are fairly ordered, and even if they wiggle around a bit and are ji

The structure comes from having a consistent configuration of the bond angles. Most proteins are fairly ordered, and even if they wiggle around a bit and are jiggly, they fold back into the same shape. However, it's not uncommon to have disordered or unstructured parts of a protein, that have no consistent shape, and are completely moveable. MYC is kind of on the extreme end of this. There's just one domain of the protein with a consistent structure, and the rest kind of conforms to the other proteins it binds to, or wiggles about. This may not be the best paper on it, but it does review a bit of the unstructured nature of MYC among lots of other stuff too: https://www.cell.com/trends/cell-biology/pdf/S0962-8924(22)00176-3.pdf https://www.cell.com/trends/cell-biology/pdf/S0962-8924(22)0...