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They are able to deform a protein involved in DNA transcription so that they can design drugs that will bind to and deactivate it. Their approach stops all DNA
by hedora 3y ago
They are able to deform a protein involved in DNA transcription so that they can design drugs that will bind to and deactivate it.
Their approach stops all DNA transcription when applied to a cell, so it’s fatal to the cell. It would also be fatal if applied to a mouse or human, except that they don’t have a way to actually deliver it outside cell cultures.
This is interesting basic research, but is far from leading to new cancer treatments.
Obligatory xkcd: https://xkcd.com/1217/ https://xkcd.com/1217/