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Along with that, the more expensive method that scales a bit easier is DNA methylation: most vertebrates, including fish, have a strong correlation between the
by a_bonobo 3y ago
Along with that, the more expensive method that scales a bit easier is DNA methylation: most vertebrates, including fish, have a strong correlation between the percentage of their genomes that has been methylated and the age. It's like r=0.99, the older, the more methylated. (however, artificially de-methylating doesn't make you younger)
So you can sequence these genomes and count. Definitely more expensive than digging out a tiny bone, but you can sequence a few hundred or thousand genomes at once.
Random example paper: https://www.nature.com/articles/s41598-023-36773-2 https://www.nature.com/articles/s41598-023-36773-2