2 ms·

Certain Gut Microbes Tied to Cognitive Function in Children

2 points by gardenfelder 3y ago

gardenfelder 3y ago
"Several microbial species were significantly enriched in children with higher cognitive function scores (eg, Alistipes obesi, Asaccharobacter celatus, Eubacterium eligens, and Faecalibacterium prausnitzii), with Sutterella wadsworthensis being the only species significantly negatively associated with these scores."
- samstave 3y ago
  It would seem that Sutterella negates the efficacy of bile in the system - so if you have a high count of Sutterella in your gut, you're likely going to suffer bile related cancers. Look at these articles - and a simple intersection summary from Bard is a good indicator to look at this bacteria - specifically due to its ability to survive in oxengenated environs - which would maybe mean liver/blood cancers... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712893/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712893/ >>>...it is possible that this bacteria could play a role in the development of bile-related cancers. Bile acids are known to damage DNA and promote cell proliferation, both of which are hallmarks of cancer. Sutterella wadsworthensis is resistant to bile acids, which suggests that it may be able to survive and even thrive in the presence of these harmful compounds. This could potentially lead to increased DNA damage and cell proliferation, and ultimately, cancer. It interferes with the bodies ability to properly process fats and such... So - targeting that bacteria could have widely beneficial outcomes. -- If you look at the following: Sutterella is indicated as being the cause of Celiac/IBS - and as bile is used to break things down into glucoses and such - it seems that basically sutterella blocks bile, and results in the body not absorbing nutrients - and basically making you nutrient defficient where youre not absorbing key nutrients as they pass through your system. THe bacteria, if related to celiac, basically would appear to be what makes the immune system attack itself in the intestines and limit the ability of villi to deal with gluten... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080374/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080374/

2 points by gardenfelder 3y ago

"Several microbial species were significantly enriched in children with higher cognitive function scores (eg, Alistipes obesi, Asaccharobacter celatus, Eubacterium eligens, and Faecalibacterium prausnitzii), with Sutterella wadsworthensis being the only species significantly negatively associated with these scores."

samstave 3y ago
It would seem that Sutterella negates the efficacy of bile in the system - so if you have a high count of Sutterella in your gut, you're likely going to suffer bile related cancers. Look at these articles - and a simple intersection summary from Bard is a good indicator to look at this bacteria - specifically due to its ability to survive in oxengenated environs - which would maybe mean liver/blood cancers... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712893/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712893/ >>>...it is possible that this bacteria could play a role in the development of bile-related cancers. Bile acids are known to damage DNA and promote cell proliferation, both of which are hallmarks of cancer. Sutterella wadsworthensis is resistant to bile acids, which suggests that it may be able to survive and even thrive in the presence of these harmful compounds. This could potentially lead to increased DNA damage and cell proliferation, and ultimately, cancer. It interferes with the bodies ability to properly process fats and such... So - targeting that bacteria could have widely beneficial outcomes. -- If you look at the following: Sutterella is indicated as being the cause of Celiac/IBS - and as bile is used to break things down into glucoses and such - it seems that basically sutterella blocks bile, and results in the body not absorbing nutrients - and basically making you nutrient defficient where youre not absorbing key nutrients as they pass through your system. THe bacteria, if related to celiac, basically would appear to be what makes the immune system attack itself in the intestines and limit the ability of villi to deal with gluten... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080374/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080374/