4 ms·

I can't tell if this is satire or not since every healthy person has probably trillions of e coli in their gut.

by umvi 3y ago

ceejayoz 3y ago
Is this satire? They’re clearly not talking about the benign strains.
- mtlmtlmtlmtl 3y ago
  The strains in your gut aren't really benign, they're just isolated to your gut. If you exposed someone to those strains by say not washing your hands before cooking, it would not be fine. I agree GP is being silly though.
  - pazimzadeh 3y ago
    Not really. Anyway the genome of E. coli is extremely diverse, there is not really such a thing as "E. coli." And strain that colonizes your gut may not colonize someone else's, or cause problems. But most living things can be opportunistic e.g. if your immune system is compromised.
    - mtlmtlmtlmtl 3y ago
      I stand corrected.
      - pazimzadeh 3y ago
        Well, you're not totally wrong since the body does have several layers of defense to keep the bacteria in the intestine, and bad things happen when they break down: https://www.pnas.org/doi/10.1073/pnas.0803124105 https://www.pnas.org/doi/10.1073/pnas.0803124105 On the other hand the immune system selects for beneficial bacteria, which take up space and nutrients so that really harmful ones can't colonize: https://sci-hub.se/10.1038/nri3535 https://sci-hub.se/10.1038/nri3535; https://www.nature.com/articles/s41586-022-05141-x https://www.nature.com/articles/s41586-022-05141-x
  - YeGoblynQueenne 3y ago
    The E. coli strains of concern are the so-called enterotoxic (or enterotoxigenic) E. coli and the Shiga-toxin producing strains. Those are not commonly found in peoples' guts and when they are, they cause... trouble. Enterotoxigenic Escherichia coli (ETEC) is a type of Escherichia coli and one of the leading bacterial causes of diarrhea in the developing world,[1] as well as the most common cause of travelers' diarrhea.[2] Insufficient data exists, but conservative estimates suggest that each year, about 157,000 deaths occur, mostly in children, from ETEC.[3][4][5] https://en.wikipedia.org/wiki/Enterotoxigenic_Escherichia_coli https://en.wikipedia.org/wiki/Enterotoxigenic_Escherichia_co... The most common sources for Shiga toxin are the bacteria S. dysenteriae and some serotypes of Escherichia coli (STEC), which includes serotypes O157:H7, and O104:H4.[4][5] Symptoms of Shiga toxin ingestion include abdominal pain as well as watery diarrhea. Severe life-threatening cases are characterized by hemorrhagic colitis (HC).[15] The toxin is associated with hemolytic-uremic syndrome. In contrast, Shigella species may also produce shigella enterotoxins, which are the cause of dysentery. https://en.wikipedia.org/wiki/Shiga_toxin https://en.wikipedia.org/wiki/Shiga_toxin
pvaldes 3y ago
> I wouldn't wish E. coli on my worst enemy Is curiously a double true. Either way you take it, there is always a possible interpretation that leads to a logical, non-satirical meaning.
pazimzadeh 3y ago
E. coli is usually less than 1% of a healthy gut flora, but yeah. It one of the first bacterias to move from the mother's vagina to the newborn baby, until it uses up the oxygen which then lets the anaerobes move in.
deleted 3y ago
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I can't tell if this is satire or not since every healthy person has probably trillions of e coli in their gut.

by umvi 3y ago

I can't tell if this is satire or not since every healthy person has probably trillions of e coli in their gut.

ceejayoz 3y ago

Is this satire? They’re clearly not talking about the benign strains.

mtlmtlmtlmtl 3y ago
The strains in your gut aren't really benign, they're just isolated to your gut. If you exposed someone to those strains by say not washing your hands before cooking, it would not be fine. I agree GP is being silly though.
- pazimzadeh 3y ago
  Not really. Anyway the genome of E. coli is extremely diverse, there is not really such a thing as "E. coli." And strain that colonizes your gut may not colonize someone else's, or cause problems. But most living things can be opportunistic e.g. if your immune system is compromised.
  - mtlmtlmtlmtl 3y ago
    I stand corrected.
    - pazimzadeh 3y ago
      Well, you're not totally wrong since the body does have several layers of defense to keep the bacteria in the intestine, and bad things happen when they break down: https://www.pnas.org/doi/10.1073/pnas.0803124105 https://www.pnas.org/doi/10.1073/pnas.0803124105 On the other hand the immune system selects for beneficial bacteria, which take up space and nutrients so that really harmful ones can't colonize: https://sci-hub.se/10.1038/nri3535 https://sci-hub.se/10.1038/nri3535; https://www.nature.com/articles/s41586-022-05141-x https://www.nature.com/articles/s41586-022-05141-x
- YeGoblynQueenne 3y ago
  The E. coli strains of concern are the so-called enterotoxic (or enterotoxigenic) E. coli and the Shiga-toxin producing strains. Those are not commonly found in peoples' guts and when they are, they cause... trouble. Enterotoxigenic Escherichia coli (ETEC) is a type of Escherichia coli and one of the leading bacterial causes of diarrhea in the developing world,[1] as well as the most common cause of travelers' diarrhea.[2] Insufficient data exists, but conservative estimates suggest that each year, about 157,000 deaths occur, mostly in children, from ETEC.[3][4][5] https://en.wikipedia.org/wiki/Enterotoxigenic_Escherichia_coli https://en.wikipedia.org/wiki/Enterotoxigenic_Escherichia_co... The most common sources for Shiga toxin are the bacteria S. dysenteriae and some serotypes of Escherichia coli (STEC), which includes serotypes O157:H7, and O104:H4.[4][5] Symptoms of Shiga toxin ingestion include abdominal pain as well as watery diarrhea. Severe life-threatening cases are characterized by hemorrhagic colitis (HC).[15] The toxin is associated with hemolytic-uremic syndrome. In contrast, Shigella species may also produce shigella enterotoxins, which are the cause of dysentery. https://en.wikipedia.org/wiki/Shiga_toxin https://en.wikipedia.org/wiki/Shiga_toxin

pvaldes 3y ago

> I wouldn't wish E. coli on my worst enemy Is curiously a double true. Either way you take it, there is always a possible interpretation that leads to a logical, non-satirical meaning.

pazimzadeh 3y ago

E. coli is usually less than 1% of a healthy gut flora, but yeah. It one of the first bacterias to move from the mother's vagina to the newborn baby, until it uses up the oxygen which then lets the anaerobes move in.

deleted 3y ago

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