If it's a ghost town because of water drying up or unfixable pollution issues (water table, air, etc...) then yes. In all other cases, small towns go through ph

If it's a ghost town because of water drying up or unfixable pollution issues (water table, air, etc...) then yes. In all other cases, small towns go through phases of ups and downs. The thing that permanently kills them is the water or pollution issue. Besides those two issues, you'll always be able to find a person willing to live out in the boonies to get away from the crazies.