3 ms·
> When researchers cloned long-tailed macaques in 2018, they created 109 cloned embryos and implanted nearly three-quarters of them into 21 surrogate monkeys, r
by Qem 3y ago
> When researchers cloned long-tailed macaques in 2018, they created 109 cloned embryos and implanted nearly three-quarters of them into 21 surrogate monkeys, resulting in six pregnancies. Just two of the monkeys survived birth.
Indeed the survival stats for cloning are abysmal.
- greggsy 3y agoI have not idea what the survival rates for a healthy monkey might be, or even an embryo for that matter, so I’m unsure what to make of these figures.
- mdorazio 3y agoThis likely has far more to do with IVF than with cloning. In humans, IVF is only 20-30% successful on the first attempt and these days it’s strongly recommended to only try one embryo at a time. Based on the numbers quoted it looks like they did 5 at a time per monkey which decreases survival rates even more. Add in average miscarriage rates in humans of 10-20% (increases with age) and this experiment doesn’t look all that bad to me.
- o11c 3y ago¾ of 109 embryos across 21 mothers is 3.8 embryos per mother. For human miscarriage rates, remember it depends heavily on how far along the pregnancy is: 70% of conceptions lead to miscarriage 50% of implantations lead to miscarriage 30% of aggressively confirmed pregnancies lead to miscarriage 15% of typical confirmed pregnancies lead to miscarriage