3 ms·
There's so many variables at play to give blanket statements. MTHFR mutations are interesting to research. I've got polymorphism (checked via a DNA test), and
by hammyhavoc 3y ago
There's so many variables at play to give blanket statements.
MTHFR mutations are interesting to research. I've got polymorphism (checked via a DNA test), and once I cut out the folic acid supplements and fortified cereals, I started feeling much better. The missus also has polymorphism, and whilst her blood results made her seem anemic, the prescribed B12 shots gave her a mental health crisis due to elevated homocysteine as a consequence.
That's not to say "supplements = bad", but having a good understanding, self-awareness and figuring out your own physiology is more important than following blanket statements said by others. This is also why some people with ADHD respond well to stimulants and others don't. People vary wildly.
- armadsen 3y agoWhat is polymorphism as you’re using the term?
- echelon 3y agoIn general: https://en.wikipedia.org/wiki/Gene_polymorphism https://en.wikipedia.org/wiki/Gene_polymorphism And with respect to this gene: https://www.ncbi.nlm.nih.gov/books/NBK6561/ https://www.ncbi.nlm.nih.gov/books/NBK6561/
- larrymcp 3y agoAnd what's this "DNS test" which diagnosed it?
- hammyhavoc 3y agoIt doesn't "diagnose", you look at what the genes express in terms of alleles. Lots of information publicly available from reputable sources. I'm not here to push recommendations of DNA services, but the better ones allow you to export your raw DNA data for further scrutiny if they don't allow you to just browse it by gene number via a web app. If you're interested, look it up. Likewise, watch out for the one that handled a security breach crappily recently.
- anemoiac 3y agoIt's always DNS!
- hammyhavoc 3y agohttps://www.healthline.com/health/mthfr-gene https://www.healthline.com/health/mthfr-gene Multiple mutations of the MTHFR gene means that a lot of blanket statement health advice doesn't necessarily apply. It's also not all that uncommon, and it's something that most docs in the UK aren't familiar with. High incidence in Ashkenazi Jews (which I am).
- deleted 3y ago[deleted]