Nowadays I am usually using micromamba inside Docker. I honestly never had any issues. I need docker anyway for deployment. And mamba/conda is almost needed for

Nowadays I am usually using micromamba inside Docker. I honestly never had any issues. I need docker anyway for deployment. And mamba/conda is almost needed for scientific stuff (working with some super niche weather stuff which is only on conda). IMO the most important thing is to stay flexible, all of them have their tradeoffs pick one that works and move to a different one if it becomes painful. Docker is very very useful though. Can you imagine the joy I felt when I spun up a 6 month old very complex project and it immediately worked.