4 ms·

What do you mean? It makes skin permeable?

tbalsam 3y ago
DMSO is terrifying, dude, it makes skin so permeable as I understand that supposedly even live bacteria outside of the skin can be transferred inside the skin. It's something I'm shocked seeing people casually use, similar to piperine. Like, with piperine, you're maximizing "absorption" by directly blocking/inhibiting the p glycoprotein pumps that pump toxic substances back into your intestine, etc. Wtf kind of short sighted thinking is that! Why is that remotely considered reasonable long term. It makes things more "absorbed" across the board. Neither is a good tool to play with, usually there is a decent, much much safer "hard way" for most of these methods in my experience, at least. :3 :)
PhasmaFelis 3y ago
DMSO goes right through skin and will carry other compounds with it. It's used in some drug delivery systems to turn an injected drug into a topical one. I first learned about it from the Shadowrun tabletop RPG. In the game, cyberpunk operatives sometimes mix DMSO with incapacitating or lethal poisons to load into military-grade squirt guns. I'm skeptical about that working IRL, but it's pretty funny.
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Modified3019 3y ago
DSMO is a solvent, a byproduct of wood processing. It can assist some molecules in passing through skin. Please note, it does not grab bacteria and pull it through skin, that’s FUDD. They are far, far too big for that. It is in fact studied as an adjuvant for antibacterial agents, as it can help antibacterial compounds penetrate bacterial biofilms. There is evidence that alone it may assist some viral activity, likely by effecting something in regards to RNA. Conversely, it may help the activity of antiviral agents by helping them penetrate deeper, preventing the strategies viruses use to hide from being as effective. I personally have no reservations to its use on skin, so long as the area is washed. Basically don’t work on your car and then apply it to your oily hands.

DMSO is terrifying, dude, it makes skin so permeable as I understand that supposedly even live bacteria outside of the skin can be transferred inside the skin. It's something I'm shocked seeing people casually use, similar to piperine. Like, with piperine, you're maximizing "absorption" by directly blocking/inhibiting the p glycoprotein pumps that pump toxic substances back into your intestine, etc. Wtf kind of short sighted thinking is that! Why is that remotely considered reasonable long term. It makes things more "absorbed" across the board. Neither is a good tool to play with, usually there is a decent, much much safer "hard way" for most of these methods in my experience, at least. :3 :)

PhasmaFelis 3y ago

DMSO goes right through skin and will carry other compounds with it. It's used in some drug delivery systems to turn an injected drug into a topical one. I first learned about it from the Shadowrun tabletop RPG. In the game, cyberpunk operatives sometimes mix DMSO with incapacitating or lethal poisons to load into military-grade squirt guns. I'm skeptical about that working IRL, but it's pretty funny.

deleted 3y ago

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Modified3019 3y ago

DSMO is a solvent, a byproduct of wood processing. It can assist some molecules in passing through skin. Please note, it does not grab bacteria and pull it through skin, that’s FUDD. They are far, far too big for that. It is in fact studied as an adjuvant for antibacterial agents, as it can help antibacterial compounds penetrate bacterial biofilms. There is evidence that alone it may assist some viral activity, likely by effecting something in regards to RNA. Conversely, it may help the activity of antiviral agents by helping them penetrate deeper, preventing the strategies viruses use to hide from being as effective. I personally have no reservations to its use on skin, so long as the area is washed. Basically don’t work on your car and then apply it to your oily hands.