from the article posted above: > The biggest factor is heat. “Higher speeds tends to produce higher temperatures and temperature is the biggest killer,” says R

from the article posted above: > The biggest factor is heat. “Higher speeds tends to produce higher temperatures and temperature is the biggest killer,” says Rita Horner, senior product marketing manager for 3D-IC at Synopsys. “Temperature exacerbates electron migration. The expected life can exponentially change from a tiny delta in temperature.” basically smaller nm builds are more susceptible to tiny variations in heat/cold, physical impacts, electrostatic shock, etc.