The evidence is fairly weak. > Although nicotine itself does not cause cancer in humans,[40] it is unclear whether it functions as a tumor promoter as of 2012.

The evidence is fairly weak. > Although nicotine itself does not cause cancer in humans,[40] it is unclear whether it functions as a tumor promoter as of 2012.[104] A 2018 report by the US National Academies of Sciences, Engineering, and Medicine concludes, "[w]hile it is biologically plausible that nicotine can act as a tumor promoter, the existing body of evidence indicates this is unlikely to translate into increased risk of human cancer."[105] https://en.wikipedia.org/wiki/Nicotine#Cancer https://en.wikipedia.org/wiki/Nicotine#Cancer In any case, it's crucial to distinguish between a weak tumor promoter which may have statistically minor impact on cancer rates (nicotine), and an unambiguous carcinogen that kills people by the bucketload (tobacco).