> "...But if you want to fix experiments in clinical medicine, this is where you start." You start by not allowing interests with a financial incentive to get

> "...But if you want to fix experiments in clinical medicine, this is where you start." You start by not allowing interests with a financial incentive to get a positive result from a clinical trial to run those trials - it's an obvious conflict of interest. However, the University of California has been a long-time leader in the exclusive licensing and privatization of discoveries made with taxpayer dollars, and so the UC also has an incentive to promote bogus clinical trials because it gets a percentage of sales from UC-licensed inventions, and so a professor at the UC who writes a screed defending these practices (which is what this article amounts to) will thereby ingratiate themselves with the administration - positive career move! The real problems come down to deliberate systematic bias in experimental design, which people outside of academia might consider to be fraud - and it should be well-understood that statistical tests have a very hard time revealing such systematic biases. Let's take a specific example - Gilead's remdesivir, and Gilead's fellowship programs and gifting to UC Berkeley professors. The corporatization of academics in the United States means that trust in the independence of academic researchers is no longer warranted, they're more in the cheerleading section now than in the rigorous science section. Thus (2021): https://pubmed.ncbi.nlm.nih.gov/34252308/ https://pubmed.ncbi.nlm.nih.gov/34252308/ > "Here, we critically evaluate the assumptions of the models underlying remdesivir's promising preclinical data and show that such assumptions overpredict efficacy and minimize toxicity of remdesivir in humans. Had the limitations of in vitro drug efficacy testing and species differences in drug metabolism been considered, the underwhelming clinical performance of remdesivir for both COVID-19 and Ebola would have been fully anticipated."