4 ms·
Am I getting this right? 1) bilirubin (from red cell breakdown) from bloodstream excreted into the gut 2) gut biota convert it to urobilinogen via bilirubin r
by pmayrgundter 3y ago
Am I getting this right?
1) bilirubin (from red cell breakdown) from bloodstream excreted into the gut
2) gut biota convert it to urobilinogen via bilirubin reductase
3) urobilinogen -> urobilin spontaneous breakdown (still in gut)
4) urobilin reabsorbed into bloodstream, filtered by kidneys, excreted in urine
If so, why not just leave it in gut for excretion with feces?
or perhaps 2.1) urobilinogen reabsorbed into bloodstream first, then 3). Makes a little more sense
- n0us 3y agoYou should bring it up to the Architecture Committee
- morkalork 3y agoWhat a bunch of fools they are, forget inefficiencies, they put waste disposal beside the recreational bits!
- saagarjha 3y agoI mean that’s not really what they were designed for were they
- nickpinkston 3y agoI think it's more that the users have historically been highly motivated and the affordances provided are optimized for broad accessibility, not core user UX. Either way, most users appeared highly engaged with the product and attempt repeat use without high churn, albeit with a lower Time on Site than the user generally wishes.
- times_trw 3y ago> Please note that homo sapiens sapiens is EOL and will not receive any security updates or bug fixes. Please update to homo sapiens sapiens sapiens as soon as possible.
- nickpinkston 3y agoI love the idea that engineering is 80% design and 20% testing, whereas evolution is 0% design and 100% testing.
- loeg 3y agoThe gut's ordinary job is to absorb nutrients from digested food.
- protomolecule 3y ago"why not just leave it in gut for excretion with feces" Because it is hard to distinguish it from nutrients?
- foxyv 3y agoProbably because the gut keeps picking up all the urobilinogen. Kinda like a hoarder when you throw their stuff out. You need another way to process that re-uptake now that it's been converted by the bacteria. Kidneys just happened to be the best man for the job.