Nerve damage does not necessarily mean irreversible consequences, depending on the degree. E.g. any amount of sleep deprivation, both in terms of quantity and q

Nerve damage does not necessarily mean irreversible consequences, depending on the degree. E.g. any amount of sleep deprivation, both in terms of quantity and quality, causes (minuscule) brain damage, but even people with severe sleep apnea mostly recover with treatment. Likewise, PDE5 inhibitors and presumably other med classes seem capable of nearly reversing mild-to-moderate nerve damage through local NGF release secondary to improved endothelial function and nerve blood supply.