"Difficult to replicate" does NOT mean "wrong". The fact that your experimental technique sucks is not my problem, thanks. Go get some better grad students.

"Difficult to replicate" does NOT mean "wrong". The fact that your experimental technique sucks is not my problem, thanks. Go get some better grad students. And this is before we start getting into medicine which has both ethical and expense issues with running multiple experiments. Your position is both unrealistic and untenable. Medicine and science would literally grind to a halt. > the incentives to cheat are obvious and there is nothing in place to prevent them. The real issue is that Marc Tessier-Lavigne has caused an entire industry to waste millions (possibly billions) of dollars,d elayed Alzheimer's research for decades and will suffer no real punishment. He's 65 years old and has made a shitload of money based on the fraud. The real question is "How do you punish this in order to disincentivize it?"