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A couple years ago I lost 80lbs in one year without any drugs. It was the hardest thing I had ever done. It required frankly extreme amounts of willpower. More

A couple years ago I lost 80lbs in one year without any drugs. It was the hardest thing I had ever done. It required frankly extreme amounts of willpower. More recently, I've lost about 25lbs on Mounjaro in two months. Zero effort. I was (quite literally) losing weight in my sleep. I never felt full/satiated before in my life eating normally before starting Ozempic. Now I understand what it means to be satiated. I wonder if this is why it was easy for me to gain and hard for me to lose weight. These drugs will be game-changers for many Americans. I think they are the solution to the obesity crisis. Now the big question: is it all priced into the stock already?

dclowd9901 3y ago
I wonder how it would work for people who have low metabolisms. I don’t eat much. Maybe twice a day, and at that, it’s usually half a ration (I’m frankly not hungry beyond that). Yet I would say I’m above a healthy weight. Maybe 20 pounds over. Not sure what this drug would do. I’ve heard it curbs appetites but if I curb my appetite anymore, I’m not eating at all.
- xvector 3y ago
  Yeah, in my experience the drug can curb appetites to somewhat dangerously low levels. I get pretty full on 650-800 cals/day and eat one meal a day. My TDEE is around 2100 cals/day. Frankly speaking, while I enjoy the weight loss, it's not healthy at this rate. This is probably just a dosage issue. Still, I can't imagine a drug that curbs appetite would be good for someone that already doesn't eat much.
- resolutebat 3y ago
  Out of curiosity, have you tried logging everything how much you eat? For me, after trying to lose weight through smaller meals and failing, cutting out all those seemingly-tiny, seemingly-healthy snacks (a handful of nuts etc) between meals is what moved the needle.
  - dclowd9901 3y ago
    Yep. I got in the habit around the time I last lost a ton of weight (about 45lbs or 20% of my weight). Only way I could do it then was working out every day and eating under 1000 calories a day. Obviously that’s not sustainable so I’ve leveled out and work out less because life.
hackernewds 3y ago
strong conviction these impacts have been telegraphed from miles away and priced in. At one point, the GDP of Norway had to be presented independently off Novo Nordisk given how massive their market cap was. Also has led to bloating of adjacent companies that should be pummeled (instead of rising) such as Weight watchers. Time will tell.
- kridsdale1 3y ago
  Denmark, but yeah. Pretty insane.
Spivak 3y ago
I'm in the same boat. I had to literally starve myself in order to lose weight and I did it but it was the most miserable experience and absolutely fucked me up mentally. My tipping point for actually losing weight is 800 calories a day with exercise, my body will kick scream and shuts down all major functions to avoid it any higher than that, I just get to be miserable with negative energy and still not lose weight. I now get to live the rest of my life with an eating disorder so that's fun but I did it I'm skinny yayyy :( I'm fiercely jealous of anyone whose metabolism let's them run a deficit and just burn fat to make up the difference instead of just passing out. Being able to just lose weight while maintaining a healthy relationship with food is going is going to be a night and day generational shift for women.
- thatfunkymunki 3y ago
  I'm the same way. Recently after a lot of painful effort, at a healthy weight after a lifetime of overweight/obesity, but at what cost to my mental health?

dclowd9901 3y ago

I wonder how it would work for people who have low metabolisms. I don’t eat much. Maybe twice a day, and at that, it’s usually half a ration (I’m frankly not hungry beyond that). Yet I would say I’m above a healthy weight. Maybe 20 pounds over. Not sure what this drug would do. I’ve heard it curbs appetites but if I curb my appetite anymore, I’m not eating at all.

xvector 3y ago
Yeah, in my experience the drug can curb appetites to somewhat dangerously low levels. I get pretty full on 650-800 cals/day and eat one meal a day. My TDEE is around 2100 cals/day. Frankly speaking, while I enjoy the weight loss, it's not healthy at this rate. This is probably just a dosage issue. Still, I can't imagine a drug that curbs appetite would be good for someone that already doesn't eat much.
resolutebat 3y ago
Out of curiosity, have you tried logging everything how much you eat? For me, after trying to lose weight through smaller meals and failing, cutting out all those seemingly-tiny, seemingly-healthy snacks (a handful of nuts etc) between meals is what moved the needle.
- dclowd9901 3y ago
  Yep. I got in the habit around the time I last lost a ton of weight (about 45lbs or 20% of my weight). Only way I could do it then was working out every day and eating under 1000 calories a day. Obviously that’s not sustainable so I’ve leveled out and work out less because life.

hackernewds 3y ago

strong conviction these impacts have been telegraphed from miles away and priced in. At one point, the GDP of Norway had to be presented independently off Novo Nordisk given how massive their market cap was. Also has led to bloating of adjacent companies that should be pummeled (instead of rising) such as Weight watchers. Time will tell.

kridsdale1 3y ago
Denmark, but yeah. Pretty insane.

Spivak 3y ago

I'm in the same boat. I had to literally starve myself in order to lose weight and I did it but it was the most miserable experience and absolutely fucked me up mentally. My tipping point for actually losing weight is 800 calories a day with exercise, my body will kick scream and shuts down all major functions to avoid it any higher than that, I just get to be miserable with negative energy and still not lose weight. I now get to live the rest of my life with an eating disorder so that's fun but I did it I'm skinny yayyy :( I'm fiercely jealous of anyone whose metabolism let's them run a deficit and just burn fat to make up the difference instead of just passing out. Being able to just lose weight while maintaining a healthy relationship with food is going is going to be a night and day generational shift for women.

thatfunkymunki 3y ago
I'm the same way. Recently after a lot of painful effort, at a healthy weight after a lifetime of overweight/obesity, but at what cost to my mental health?