I don't know if multiple antibiotics helps prevent resistance necessarily. Resistance usually comes about when the dosage given allows survivors with resistanc

I don't know if multiple antibiotics helps prevent resistance necessarily. Resistance usually comes about when the dosage given allows survivors with resistance mutations to become the main population. I mean, I can see where multiple antibiotics and sub-lethal dosages that disrupt function in multiple ways could be enough pressure to break the bacteria, but sufficient dosing is important, and making sure a patient does their regimen properly is entirely the patient's responsibility. In order to prevent the exact same situation playing out with any new antibiotics, we shouldn't allow history to repeat itself. Plus the normal gut flora would be disrupted by the multiple antibiotics as well, so there would be more work involved in the recovery of the symbiotes and commensals.