5 ms·

Tigecycline https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1426172/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1426172/ is a new class of antibiotics discover

Tigecycline https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1426172/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1426172/ is a new class of antibiotics discovered around 2005 that also works against resistant bacteria such as MRSA and VRE. So while it is great they are coming up with new antibiotics, it is by no means the first in 60 years.

pajko 3y ago
Ceftaroline https://pubmed.ncbi.nlm.nih.gov/20334458/ https://pubmed.ncbi.nlm.nih.gov/20334458/ Discovered about at the same time or later. Also works against MRSA.
PlasmonOwl 3y ago
Had the same issue on Reddit recently. Toxibaccin was discovered in soils in 2018. Hell I know someone who developed one recently at a university. It’s AMAZING AI can do this, but it certainly doesn’t destroy prior approaches. Yet. Disclaimer: spelling and name of antibiotic may be incorrect. It is not my field, and the spelling is phonetic from myself. If pressed, I will ask the scientist for the specific name.
- maxerickson 3y ago
  I expect you are referencing https://en.wikipedia.org/wiki/Teixobactin https://en.wikipedia.org/wiki/Teixobactin
  - 29athrowaway 3y ago
    Discovered in some random dirt from Maine.
    - hackernewds 3y ago
      "Discovered" like penicillin? It irks me when it's presented as accidental, when it does go through testing after
      - 29athrowaway 3y ago
        Penicillin was also accidental? I don't understand the point.
        PlasmonOwl 3y ago
        Maybe he conflates discovery with accident. Materials science searches chemical space and makes discoveries. There is no accident in that kind of discovery?
maxerickson 3y ago
Seems that is a tetracycline derivative? A class of antibiotics generally refers to the mechanism of action, so I'd think it wouldn't be a new class if it is derived from an existing one.
awwaiid 3y ago
Maybe this is a missing-comma type issue, and they mean that the last time that AI came up with an antibiotic was 60 years ago
- augustulus 3y ago
  where would you put the comma to fix that?
  - lacrimacida 3y ago
    It’s the first comma in click-bait.
hackernewds 3y ago
now for them to make one against viruses

pajko 3y ago

Ceftaroline https://pubmed.ncbi.nlm.nih.gov/20334458/ https://pubmed.ncbi.nlm.nih.gov/20334458/ Discovered about at the same time or later. Also works against MRSA.

PlasmonOwl 3y ago

Had the same issue on Reddit recently. Toxibaccin was discovered in soils in 2018. Hell I know someone who developed one recently at a university. It’s AMAZING AI can do this, but it certainly doesn’t destroy prior approaches. Yet. Disclaimer: spelling and name of antibiotic may be incorrect. It is not my field, and the spelling is phonetic from myself. If pressed, I will ask the scientist for the specific name.

maxerickson 3y ago
I expect you are referencing https://en.wikipedia.org/wiki/Teixobactin https://en.wikipedia.org/wiki/Teixobactin
- 29athrowaway 3y ago
  Discovered in some random dirt from Maine.
  - hackernewds 3y ago
    "Discovered" like penicillin? It irks me when it's presented as accidental, when it does go through testing after
    - 29athrowaway 3y ago
      Penicillin was also accidental? I don't understand the point.
      - PlasmonOwl 3y ago
        Maybe he conflates discovery with accident. Materials science searches chemical space and makes discoveries. There is no accident in that kind of discovery?

maxerickson 3y ago

Seems that is a tetracycline derivative? A class of antibiotics generally refers to the mechanism of action, so I'd think it wouldn't be a new class if it is derived from an existing one.

awwaiid 3y ago

Maybe this is a missing-comma type issue, and they mean that the last time that AI came up with an antibiotic was 60 years ago

augustulus 3y ago
where would you put the comma to fix that?
- lacrimacida 3y ago
  It’s the first comma in click-bait.

hackernewds 3y ago

now for them to make one against viruses