I used to do the same thing he describes. I had a core2duo in one PC and an i7 in the other. Both powered by Nvidia graphics and on 64bit OS'es. Both Linux (

I used to do the same thing he describes. I had a core2duo in one PC and an i7 in the other. Both powered by Nvidia graphics and on 64bit OS'es. Both Linux (arch) and Windows 7 worked without a complaint when swapping hard disk between the two. I do remember that back in the days you'd get an instant blue screen as soon as you change anything important hardware related on your rig. The only risk factor I can see is that the hard drive might get damaged during transport.