I'm someone who has suffered from post-viral ME/CFS, so I know how devastating it is. However, there isn't any evidence that EBV reactivation causes symptoms. (

I'm someone who has suffered from post-viral ME/CFS, so I know how devastating it is. However, there isn't any evidence that EBV reactivation causes symptoms. (Initial mono infection is different). - multiple studies in ME/CFS patients, even ones with EBV reactivation, show that antivirals aren't helpful. - students studying for exams and astronauts have high EBV titers (signifying reactivation), but they don't have any kind of ME/CFS symptoms. EBV reactivation is just a symptom, caused by stress. It doesn't seem to be central to the illness itself.