I'm not terribly well versed with nginx, but the creator mentions only support for .htaccess, I was able to get this working with the following in my config for

I'm not terribly well versed with nginx, but the creator mentions only support for .htaccess, I was able to get this working with the following in my config for nginx: if ($request_filename !~* ai-cache) { rewrite \.(?:jpe?g|gif|png)$ /adaptive-images.php last; }