3 ms·
> This sensory neuropathy usually develops at doses of pyridoxine above 1000 mg per day. There are some case reports of sensory neuropathies at doses of less th
by frankjr 3y ago
> This sensory neuropathy usually develops at doses of pyridoxine above 1000 mg per day. There are some case reports of sensory neuropathies at doses of less than 500 mg per day in patients taking supplements for months. However, none of the studies had sensory nerve damage at a daily intake below 200 mg of pyridoxine per day.
Those are some extreme numbers. How do you even take 1000 mg per day? The supplements I take contain 1.4 mg in the daily dose.
- walterbell 3y agoAustralian regulator has a much lower threshold: Due to the risk of peripheral neuropathy, products that contain more than 50 mg are required to have the following warning displayed on the product label: 'WARNING - Stop taking this medication if you experience tingling, burning or numbness and see your healthcare practitioner as soon as possible. (Contains vitamin B6)' The TGA is aware of recent reports, both in Australia and overseas, which indicate that peripheral neuropathy may occur: - at a daily dose of less than 50 mg a day of vitamin B6 - in consumers taking more than one product containing vitamin B6