I get what you are saying, but in some domains, you really do design for a single SKU, beyond even just the CPU. Supercomputers and computing centers like SLAC

I get what you are saying, but in some domains, you really do design for a single SKU, beyond even just the CPU. Supercomputers and computing centers like SLAC have a very constrained set of SKUs that your software will ever run on. I know this is not how most cloud or consumer software works, but that stuff usually isnt as performance-sensitive.