I read a number of studies one time after a trip back home to Florida left me itching everywhere. Surprisingly, it seemed that the strongest evidence by far was

I read a number of studies one time after a trip back home to Florida left me itching everywhere. Surprisingly, it seemed that the strongest evidence by far was for topical ammonia, with antihistamines, heat, cold, and other common remedies showing limited effectiveness. Ammonia is a rather unpleasant choice, but I've also found that Windex makes short work of cockroaches that laugh at Raid and the like. From my experience, the best defense against mosquito itch is living in Florida -- you rapidly become resistant, and eventually the bites fade within a couple hours. However, this has other downsides.