2 ms·
They do go away, but it depends on numerous factors. In humans, if you have polymorphisms in various genes relating to GSH detoxification, the half life could i
by monkburger 3y ago
They do go away, but it depends on numerous factors. In humans, if you have polymorphisms in various genes relating to GSH detoxification, the half life could increase. (in theory)
half-lives of long-chain PFAS were longer than those of short-chain compounds, reaching almost 3 years in some cases. Some studies estimated the average half-lives for PFHxS at 2.86 years and L-PFOS (a specific form of perfluorooctane sulfonic acid, C8) at 2.91 years. In comparison, the short-chain PFPeS had an estimated average half-life of 0.63 years, and perfluoroheptane sulfonic acid (PFHpS, C7) concentrations were 1.46 years. The shortest estimated half-lives were for perfluorobutanoic acid (PFBA, C4) at 0.12 years and perfluoroheptanoic acid (PFHpA, C7) at 0.17 years.
- ornornor 3y agoDoes this mean that if we stopped producing any new forever chemicals today, it would take more or less three years for organisms to expel them from their systems? Are they destroyed or simply taken out of the organisms and ready to be reabsorbed by the same or another organism for ever?
- monkburger 3y agoEnvironmental half lives are a different animal. I vaguely recall some obs studies that estimate a half life of PFOA to be 90 (water), 114 days for PFOS, their half-life in water is greater than 90 years for PFOA and greater than 41 years for PFOS, according to a 2014 publication from the EPA. There's also a study from Europe showing vastly different half-lives based on soil temperature (colder temps -> longer half life), but I cannot locate the paper at the moment. US EPA. (2014). Emerging Contaminants Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoic Acid (PFOA), https://www.wqa.org/Portals/0/Government%20Relations/factsheet_contaminant_pfos_pfoa_m https://www.wqa.org/Portals/0/Government%20Relations/factshe... arch2014.pdf