Medical research, especially pre-clinical, stands shoulder to shoulder with social psychology in terms of replication rates. Wiki has a brief paragraph on it on

Medical research, especially pre-clinical, stands shoulder to shoulder with social psychology in terms of replication rates. Wiki has a brief paragraph on it on their replication crisis page [1], but this [2] page does a far better job of conveying and citing all sorts of interesting data and studies. The pathway to profit for medicine is getting the FDA to approve your drug. This should only happen if the drug works, but the way the FDA determines that is by the data and studies you give them. Well at least in theory, there's also complete nonsense like aduhelm where the FDA even approved a drug their own medical panel concluded didn't work, leading to mass protest resignations. [3] That's probably an argument against shenanigans (why even bother?), but I still think it's relevant just to emphasize how dysfunctional our medical regulatory system has become. [1] - https://en.wikipedia.org/wiki/Replication_crisis#In_medicine https://en.wikipedia.org/wiki/Replication_crisis#In_medicine [2] - https://www.taconic.com/taconic-insights/quality/replication-crisis-preclinical-research.html https://www.taconic.com/taconic-insights/quality/replication... [3] - https://www.nytimes.com/2021/07/19/health/alzheimers-drug-aduhelm-fda.html https://www.nytimes.com/2021/07/19/health/alzheimers-drug-ad...