4 ms·
This seems unsurprising? CAR-T is engineered to kill of CD19 expressing immune cells. I’m sure you could take b-cell depleting antibodies as well and have it
by refurb 3y ago
This seems unsurprising?
CAR-T is engineered to kill of CD19 expressing immune cells.
I’m sure you could take b-cell depleting antibodies as well and have it push your autoimmune disease into remission. And they are already used to treat autoimmune diseases like MS, Crohn’s, etc.
But depleting immune cells comes with a host of side effects. Risk of infection, even diseases that you’d otherwise easily fight off.
- ajhurliman 3y agoYou could call the b-cell strategy CAR-T B (sorry for the terrible pun)
- phone8675309 3y ago> But depleting immune cells comes with a host of side effects. Risk of infection, even diseases that you’d otherwise easily fight off Some people with autoimmune disorders have to take immunosuppressors so they already have that risk of infection.