3 ms·
This is similar to DMT: https://www.pnas.org/doi/10.1073/pnas.2218949120 https://www.pnas.org/doi/10.1073/pnas.2218949120 > Consistent with previous DMT study
by dj_mc_merlin 3y ago
This is similar to DMT:
https://www.pnas.org/doi/10.1073/pnas.2218949120 https://www.pnas.org/doi/10.1073/pnas.2218949120
> Consistent with previous DMT study findings (32, 39), static analyses revealed widespread decreases in alpha power under DMT (P < 0.01, cluster corrected), and increases in both delta (P < 0.05, cluster corrected) and gamma bands (P < 0.01, cluster corrected).
DMT and otherpsychedelics are also influenced by glutamate:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547711/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547711/
> Following a double-blind, placebo-controlled, parallel group design, we utilized an ultra-high field multimodal brain imaging approach and demonstrated that psilocybin (0.17 mg/kg) induced region-dependent alterations in glutamate, which predicted distortions in the subjective experience of one’s self (ego dissolution). Whereas higher levels of medial prefrontal cortical glutamate were associated with negatively experienced ego dissolution, lower levels in hippocampal glutamate were associated with positively experienced ego dissolution.
Other forces seem at play as well. When I almost drowned I definitely experienced positive ego dissolution -- you feel at peace with the idea you might die. So it can't be that simple.