> And remember - we did have a long experiment with legally prescribed opioids, and their widespread availability contributed to the current addiction crisis.

> And remember - we did have a long experiment with legally prescribed opioids, and their widespread availability contributed to the current addiction crisis. That is not what "legalized" means. It's still illegal to have opioids from anywhere other than your own prescription, which means that people without a prescription are basically on their own, have to get it through illegitimate means, and are all the way back to not knowing what they're getting. If I wanted a supply of, say, LSD, I am not going to accept a doctor telling me how much I can have, when and where I can have it (as in current legalized psilocybin clinics). I want to buy some from the store, take it home, and enjoy it in my own, safe environment, with friends and people I can trust. Is that so hard to ask? It's not like it's any less safe than stuff like alcohol or tobacco, in fact there isn't even any known LD50 yet. The only risk is things being sold as LSD that aren't actually, which is basically the same scenario as the current opioid crisis.