3 ms·

What about the effects of an extremely wide and extremely quick deployment of a novel vaccine (under threat of being fired)?

throwawayq3423 3y ago
What does "novel vaccine" mean?
- zmgsabst 3y ago
  That we haven’t used mRNA gene therapies to treat a virus before.
  - lostlogin 3y ago
    Maybe not that widely, but the technique seems to have had prior usage. https://en.m.wikipedia.org/wiki/MRNA_vaccine https://en.m.wikipedia.org/wiki/MRNA_vaccine
    - mikrotikker 3y ago
      In bovines yes. And they laughed at Joe Rogan for using "horse medicine"
      - throwawayq3423 3y ago
        It's been studied intensely since its discovery in the 1990s, it's not in any way a "brand new" technology.
- defrost 3y ago
  A vaccine that had a significant impact on a notable percentage of the population 24 months before widespread uptake. The Thiotimoline of vaccines. https://commons.wikimedia.org/wiki/File:Historical_Average_ACT_Scores.svg https://commons.wikimedia.org/wiki/File:Historical_Average_A... https://en.wikipedia.org/wiki/Thiotimoline https://en.wikipedia.org/wiki/Thiotimoline
  - defrost 3y ago
    Spelling this out slowly for the reflexive downvoters, ACT test scores began their decline well before any widespread use of mRNA COVID vaccines which would make them extremely novel in their endochronicity if they had an effect before they were used. Otherwise, as pointed out by lostlogin, mRNA vaccines have been used in humans since 2013 and studied in animals since 1989 which makes them less novel than widely claimed.
    - astrange 3y ago
      Your problem is thiotimoline sounds too much like thalidomide, the thing that made the FDA proud of their excessively strict medication regulations.
aredox 3y ago
What about the effects of repeat infections by a very contagious and neuro invasive novel virus? Hmmm?
- mikrotikker 3y ago
  Yes also that.
astrange 3y ago
Amazingly enough, it turns out it's easier to test a vaccine when there's a pandemic happening. Since vaccine testing requires giving half your study population a placebo and then waiting for them to get sick. Bit cruel really.

throwawayq3423 3y ago

What does "novel vaccine" mean?

zmgsabst 3y ago
That we haven’t used mRNA gene therapies to treat a virus before.
- lostlogin 3y ago
  Maybe not that widely, but the technique seems to have had prior usage. https://en.m.wikipedia.org/wiki/MRNA_vaccine https://en.m.wikipedia.org/wiki/MRNA_vaccine
  - mikrotikker 3y ago
    In bovines yes. And they laughed at Joe Rogan for using "horse medicine"
    - throwawayq3423 3y ago
      It's been studied intensely since its discovery in the 1990s, it's not in any way a "brand new" technology.
defrost 3y ago
A vaccine that had a significant impact on a notable percentage of the population 24 months before widespread uptake. The Thiotimoline of vaccines. https://commons.wikimedia.org/wiki/File:Historical_Average_ACT_Scores.svg https://commons.wikimedia.org/wiki/File:Historical_Average_A... https://en.wikipedia.org/wiki/Thiotimoline https://en.wikipedia.org/wiki/Thiotimoline
- defrost 3y ago
  Spelling this out slowly for the reflexive downvoters, ACT test scores began their decline well before any widespread use of mRNA COVID vaccines which would make them extremely novel in their endochronicity if they had an effect before they were used. Otherwise, as pointed out by lostlogin, mRNA vaccines have been used in humans since 2013 and studied in animals since 1989 which makes them less novel than widely claimed.
  - astrange 3y ago
    Your problem is thiotimoline sounds too much like thalidomide, the thing that made the FDA proud of their excessively strict medication regulations.

aredox 3y ago

What about the effects of repeat infections by a very contagious and neuro invasive novel virus? Hmmm?

mikrotikker 3y ago
Yes also that.

astrange 3y ago

Amazingly enough, it turns out it's easier to test a vaccine when there's a pandemic happening. Since vaccine testing requires giving half your study population a placebo and then waiting for them to get sick. Bit cruel really.