4 ms·

Absorption is poor sublingually and is limited by https://en.m.wikipedia.org/wiki/Intrinsic_factor https://en.m.wikipedia.org/wiki/Intrinsic_factor so I wouldn’

by geeB 3y ago

Absorption is poor sublingually and is limited by https://en.m.wikipedia.org/wiki/Intrinsic_factor https://en.m.wikipedia.org/wiki/Intrinsic_factor so I wouldn’t be surprised if most of those doses just get destroyed in the stomach

mthoms 3y ago
I have exactly that problem - malabsorption. The sublingual tablets have helped considerably. I’m just trying to understand why the other commenter considers the dose mention as “high”. I’ve never heard that claimed before.
- _xerces_ 3y ago
  I was referring to multivitamin levels which are typically ~100% RDA, so to get the levels the study considered harmful, you have to be intentionally taking large doses of B Vitamins which is easy not to do.
  - ty4smoking 3y ago
    Some Caffeine Shots include very high doses of B6 and B12 vitamins. ## 2023-12: B6/B12 RDVs, RDV % Supplement Facts inconsistencies 5-Hour Energy nutrition facts: https://www.google.com/search?q=5+hour+energy+nutrition+facts https://www.google.com/search?q=5+hour+energy+nutrition+fact... : > B6: 40mg: 2000% RDV > B12: 500mcg: 8333% RDV 5-Hour Energy Extra Strength: > B6: 40mg: 2353% > B12: 500mcg: 20833% Summit Red Thunder Energy Shot nutrition facts: https://www.google.com/search?q=Summit+Red+Thunder+Energy+Shot+nutrition+facts https://www.google.com/search?q=Summit+Red+Thunder+Energy+Sh... > Kirkland Signature Extra Strength: > B6: 40mg: 2533% RDV > B12: 500mcg: 20833% RDV ... Again, /? b6 b12 male smokers https://www.google.com/search?q=b6+b12+male+smokers https://www.google.com/search?q=b6+b12+male+smokers "Long-Term, High-Dose Vitamin B6/B12 Use Associated With Increased Lung Cancer Risk Among Men" (2023) https://cancer.osu.edu/news/long-term-high-dose-vitamin-b6-b12-use-associated-with-increased-lung-cancer-risk-among-men https://cancer.osu.edu/news/long-term-high-dose-vitamin-b6-b...

by geeB 3y ago

mthoms 3y ago

I have exactly that problem - malabsorption. The sublingual tablets have helped considerably. I’m just trying to understand why the other commenter considers the dose mention as “high”. I’ve never heard that claimed before.

_xerces_ 3y ago
I was referring to multivitamin levels which are typically ~100% RDA, so to get the levels the study considered harmful, you have to be intentionally taking large doses of B Vitamins which is easy not to do.
- ty4smoking 3y ago
  Some Caffeine Shots include very high doses of B6 and B12 vitamins. ## 2023-12: B6/B12 RDVs, RDV % Supplement Facts inconsistencies 5-Hour Energy nutrition facts: https://www.google.com/search?q=5+hour+energy+nutrition+facts https://www.google.com/search?q=5+hour+energy+nutrition+fact... : > B6: 40mg: 2000% RDV > B12: 500mcg: 8333% RDV 5-Hour Energy Extra Strength: > B6: 40mg: 2353% > B12: 500mcg: 20833% Summit Red Thunder Energy Shot nutrition facts: https://www.google.com/search?q=Summit+Red+Thunder+Energy+Shot+nutrition+facts https://www.google.com/search?q=Summit+Red+Thunder+Energy+Sh... > Kirkland Signature Extra Strength: > B6: 40mg: 2533% RDV > B12: 500mcg: 20833% RDV ... Again, /? b6 b12 male smokers https://www.google.com/search?q=b6+b12+male+smokers https://www.google.com/search?q=b6+b12+male+smokers "Long-Term, High-Dose Vitamin B6/B12 Use Associated With Increased Lung Cancer Risk Among Men" (2023) https://cancer.osu.edu/news/long-term-high-dose-vitamin-b6-b12-use-associated-with-increased-lung-cancer-risk-among-men https://cancer.osu.edu/news/long-term-high-dose-vitamin-b6-b...