Every time I read[1] about CRISPR there seem to be concerns about off-target editing, that might cause all kinds of trouble. Is this a solved issue ? Note: I a

Every time I read[1] about CRISPR there seem to be concerns about off-target editing, that might cause all kinds of trouble. Is this a solved issue ? Note: I am not a doctor, but I do have a genetic condition that might benefit from CRISPR therapies, hence my interest. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034092/#:~:text=Although%20CRISPR%2FCas%20systems%20exhibit,may%20lead%20to%20adverse%20outcomes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034092/#:~:te....