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F@H is a physics simulation. It is going to get closer to truth as we understand it. AlphaFold is going to be more pattern matching based on previously identifi
by 0cf8612b2e1e 3y ago
F@H is a physics simulation. It is going to get closer to truth as we understand it. AlphaFold is going to be more pattern matching based on previously identified relationships.
AF did a tremendous amount of work in patching up our spotty structure database, but those hairy, novel regions are still going to require extensive computation to model, which is better done by simulation.