It's not inherently sexist to point out differences between sexes, especially in context that isn't discriminatory. There are also practical differences due to

It's not inherently sexist to point out differences between sexes, especially in context that isn't discriminatory. There are also practical differences due to environment and culture, not biology. In case of games, usually the problem is that the stories are written from a perspective of a male fantasy, where role of women is reduced to just being a pretty accessory. "Dead hooker" jokes aren't equally funny to everyone. Whether this game will be more appealing to women remains to be seen. It's not merely about having a female-looking avatar, but about having an intereresting character that women would want to see themselves as, and not feel objectified (which games sometimes fail with things like bikini armor, or on the other end overdoing the trope of a "strong female character" to the point of being a boring cliche).