Yes. I successfully set up for my Mom, an Echo device with Alexa, it responds to her commands, it makes and receives calls through Skype, it plays Audible book

Yes. I successfully set up for my Mom, an Echo device with Alexa, it responds to her commands, it makes and receives calls through Skype, it plays Audible books, Podcasts, and a bunch of Alexa skills. Also, it can access nfb.org with timely access to many newspapers and magazines across the United States.