I think the limiting factor to growth of the startup culture is the fact that big organizations are good at providing commodity goods and services and the freed

I think the limiting factor to growth of the startup culture is the fact that big organizations are good at providing commodity goods and services and the freedom and unconventional nature of startups doesn't seem to scale up to big organizations. At some point I'm sure even companies like Google and Genentech, which tried to maintain the startup feeling, start to feel pretty corporate. So I would agree insofar as to say that startups will become the de facto standard method of commercializing new technology, but I don't think they will ever represent a significant portion of the economy as far as the number of people employed. Having such a small percentage of the population involved in startups doesn't afford them much opportunity to affect social norms on a large scale. Short of complete automation, big organizations will always be best at doing commodity things like picking up your trash and making your shirts. Even once those particular tasks are automated, big organizations will grow (often from startups) elsewhere to tackle new commodity goods and services. Once something is no longer cutting edge, it'll be provided by a big organization. Startups will always disrupt the way big organizations currently do things, but by being successful they will just become big organizations themselves.